Traumatic brain injury (TBI) results from external mechanical force to the head, ranging from mild (concussion) to severe (prolonged loss of consciousness, structural brain damage). TBI affects an estimated 69 million people worldwide annually and is a leading cause of disability and death in young adults. The cognitive consequences of TBI have been critically important for understanding brain-behavior relationships — historically through case studies and now through systematic neuropsychological assessment of large patient populations.
Cognitive Consequences
TBI commonly produces deficits in attention (slowed processing speed, difficulty concentrating, increased distractibility), memory (particularly encoding new information, while remote memories are often preserved), and executive function (planning, organization, impulse control, cognitive flexibility). The severity and pattern of deficits depend on the location and extent of damage. Focal injuries produce specific deficits related to the damaged area, while diffuse axonal injury — widespread shearing of white matter connections — produces more generalized slowing and attentional difficulties.
Mild TBI (concussion) typically produces temporary cognitive symptoms (confusion, memory gaps, slowed thinking) that resolve within weeks to months. However, research on chronic traumatic encephalopathy (CTE) has revealed that repeated mild TBIs — common in contact sports and military service — can produce progressive neurodegeneration with cognitive, mood, and behavioral symptoms appearing years or decades later. This has led to major changes in sports concussion protocols and increased attention to brain health in contact sports.
Recovery and Rehabilitation
Neural plasticity enables significant recovery after TBI, particularly in the first year. Cognitive rehabilitation involves both restorative approaches (exercises to improve impaired functions) and compensatory strategies (external aids, environmental modifications). Neuropsychological assessment plays a central role in characterizing deficits, tracking recovery, and designing individualized rehabilitation programs.